Table 3. Histology of resected cancersa.
| Confirmed resection status | Number (%) |
| R0 | 67 (82%) |
| R1 | 8 (10%) |
| R2 | 1 (1%) |
| Did not have surgery | 6 (7%) |
| Tumour regression grade | Number (%) |
| Grade 0 | 10 (12%) |
| Grade 1 | 11 (13%) |
| Grade 2 | 18 (22%) |
| Grade 3 | 17 (21%) |
| Grade 4 | 6 (7%) |
| Grade 5: pCR | 14 (17%) |
| Did not have surgery | 6 (7%) |
| T stage | Number (%) |
| ypT0 | 14 (17%) |
| ypT1 | 1 (1%) |
| ypT2 | 17 (21%) |
| ypT3 | 40 (49%) |
| ypT4 | 3 (4%) |
| ypTx | 1 (1%) |
| Did not have surgery | 6 (7%) |
| N stage | Number (%) |
| ypN0 | 52 (63%) |
| ypN1 | 15 (18%) |
| ypN2 | 9 (11%) |
| Did not have surgery | 6 (7%) |
| T stage of resected specimen compared to pre-treatment MRI scan | Number (%) |
| Downstaged | 37 (49%) |
| Unchanged | 33 (44%) |
| Upstaged | 5 (7%) |
| Total | 75 (100%) |
| N stage of resected specimen compared to pre-treatment MRI scan | Number (%) |
| N1-2 downstaged | 50 (78%) |
| N1-2 unchanged | 12 (19%) |
| N1-2 upstaged | 2 (3%) |
| Total | 64 (100%) |
| N0 unchanged | 9 (75%) |
| N0 upstaged | 3 (25%) |
| Total | 12 (100%) |
Abbreviations: CRT=chemoradiation; MRI=magnetic resonance imaging.
a
82 patients were recruited to EXCITE in total and six patients did not have surgery because two patients did not commence CRT and in 4 patients a ‘wait and watch’ approach was adopted by the treating team because of a complete clinical response to CRT.