Table 1.

Summary of the In Vitro Characterization Data.

Compound	Molecular Formula	MW (calcd) /g/mola	Specific activity / GBq/μmol	LogD (n-octanol: PBS pH7.4)	K d / nmol/L
68Ga-1	C44H58GaN6O17S2 –	1075.2561	42.2	−4.06 ± 0.10	2.89 ± 0.55
68Ga-4	C47H79GaN10O18	1140.4830	27.4	−3.24 ± 0.05	26.4 ± 7.8
68Ga-7	C51H81GaN12O16S2	1250.4591	23.8	−2.60 ± 0.02	13.6 ± 2.6

Abbreviations: ⁶⁸Ga-1, ⁶⁸Ga-HBED-CC-PSMA; ⁶⁸Ga-4, ⁶⁸Ga-DFO-Nsucc-PSMA; ⁶⁸Ga-768, Ga-DFO-pNCS-Bn-PSMA; PSMA, prostate-specific membrane antigen.

^aExact isotopic mass.