Skip to main content
. 2017 Oct 23;51(6):1674–1684. doi: 10.3892/ijo.2017.4177

Figure 2.

Figure 2

The antiproliferative effects of telmisartan in CCA cells are mediated via cell cycle arrest. (A) HuCCT-1 cells treated with or without 100 µM were analyzed by flow cytometry to estimate the amount of cells in each phase of the cell cycle. (B) The histogram represents the percentage of cells in each cell cycle phase. Telmisartan blocked the cell cycle at G0-G1. (*P<0.05, **P<0.01, vs. control). (C) Expression of cyclin D1, Cdk4, Cdk6, cyclin E, Cdk2, phosphory-lated Rb (pRb) and Rb, in HuCCT-1 cells at 24 and 48 h after the addition of 100 µM telmisartan as analyzed by western blotting.