Table I.

Statistical analysis results and chromosomal locations of miRNAs in HuCCT-1 cells treated with and without telmisartan.

MicroRNAs	Fold-changea	P-value	Chromosomal localization
Upregulated
hsa-miR-6088	2.41	0.0087	19q13.32
hsa-miR-6131	2.27	0.0050	5p15.2
hsa-miR-4485-3p	2.02	0.0050	11
hsa-miR-3178	1.63	0.0050	16p13.3
hsa-miR-6768-5p	1.54	0.0049	16
hsa-miR-4488	1.51	0.0050	11
hsa-miR-3651	1.48	0.0022	9
hsa-miR-4730	1.48	0.0260	17
hsa-miR-203a-3p	1.48	0.0200	14q32.33
hsa-miR-23b-3p	1.46	0.0114	9q22.32
hsa-miR-29a-3p	1.45	0.0025	7q32.1
hsa-miR-205-5p	1.43	0.0129	1q32.2
hsa-miR-4466	1.43	0.0049	6
hsa-miR-6724-5p	1.42	0.0047
hsa-miR-4324	1.39	0.0050	19
hsa-miR-138-5p	1.39	0.0049
hsa-miR-455-3p	1.39	0.0101	9q32
hsa-miR-146a-5p	1.38	0.0103	5q33.3
hsa-miR-6784-5p	1.37	0.0063	17
hsa-miR-1469	1.37	0.0022	15q26.2
hsa-miR-23a-3p	1.34	0.0056	19p13.13
hsa-miR-6869-5p	1.34	0.0129	20
hsa-miR-8059	1.31	0.0159	17
hsa-let-7i-5p	1.31	0.0123	12q14.1
hsa-miR-193a-3p	1.31	0.0050	17q11.2
hsa-miR-6780b-5p	1.3	0.0043	17
hsa-miR-658	1.3	0.0124	22q13.1
hsa-miR-1973	1.29	0.0049	4
hsa-miR-6786-5p	1.29	0.0050	17
hsa-miR-3940-5p	1.29	0.0050	19
hsa-miR-3656	1.27	0.0127	11
hsa-miR-29b-3p	1.23	0.0484	3
hsa-miR-6727-5p	1.23	0.0046	1
hsa-miR-5787	1.23	0.0235	3
hsa-miR-100-5p	1.22	0.0043	11q24.1
hsa-miR-24-3p	1.22	0.0354	8
hsa-miR-638	1.22	0.0043	19p13.2
Downregulated
hsa-miR-4284	0.43	0.0044	7
hsa-miR-425-5p	0.5	0.0049	3p21.31
hsa-miR-222-5p	0.51	0.0050	Xp11.3
hsa-miR-4521	0.56	0.0049	1
hsa-miR-452-5p	0.57	0.0022	Xq28
hsa-miR-192-5p	0.57	0.0050	11q13.1
hsa-miR-4484	0.58	0.0050	10
hsa-miR-330-3p	0.58	0.0046	19q13.32
hsa-miR-194-5p	0.6	0.0022
hsa-miR-191-5p	0.61	0.0048	3p21.31
hsa-miR-345-5p	0.61	0.0047	14q32.2
hsa-miR-4448	0.62	0.0022	3q27.1
hsa-miR-484	0.65	0.0022	16p13.11
hsa-miR-5100	0.66	0.0048	10q11.21
hsa-miR-210-3p	0.66	0.0049	11p15.5
hsa-miR-148b-3p	0.67	0.0064	12q13.13
hsa-miR-584-5p	0.69	0.0050	5q32
hsa-miR-224-5p	0.7	0.0050	Xq28
hsa-miR-1233-5p	0.71	0.0050	15
hsa-miR-301a-3p	0.71	0.0050	17q22
hsa-miR-619-5p	0.71	0.0050	12q24.11
hsa-miR-7977	0.71	0.0023	3
hsa-miR-130a-3p	0.71	0.0035	11q12.1
hsa-miR-7114-5p	0.72	0.0022	9
hsa-miR-130b-3p	0.72	0.0049	22
hsa-miR-106b-5p	0.73	0.0048	7q22.1
hsa-miR-324-5p	0.73	0.0022	17p13.1
hsa-miR-181d-5p	0.74	0.0064	19p13.13
hsa-miR-1913	0.74	0.0087	6
hsa-miR-140-3p	0.75	0.0087	16q22.1
hsa-miR-17-3p	0.75	0.0048	13q31.3
hsa-miR-128-3p	0.76	0.0043
hsa-miR-141-3p	0.76	0.0100	12p13.31
hsa-miR-331-3p	0.76	0.0129	12q22
hsa-miR-25-3p	0.76	0.0077	7q22.1
hsa-miR-96-5p	0.76	0.0048	7q32.2
hsa-miR-4286	0.77	0.0048	8
hsa-miR-18b-5p	0.77	0.0049	Xq26.2
hsa-miR-181b-5p	0.78	0.0064
hsa-miR-18a-5p	0.78	0.0063	13q31.1
hsa-miR-3607-5p	0.78	0.0303	5q14.3
hsa-miR-4664-5p	0.79	0.0087	8
hsa-miR-454-3p	0.81	0.0049	17q22
hsa-miR-6840-3p	0.82	0.0079	7
hsa-miR-3135b	0.82	0.0367	6

^aFold-change is telmisartan treated/non-treated. Fold change (FC) >1.2, FC <0.83, P-value <0.05.