Table II.
Differential expression of HOTTIP of clinicopathological parameters in HCC tissue based on TCGA database.
| Clinicopathological features | N | HOTTIP expression
|
||
|---|---|---|---|---|
| Mean ± SD | T | P-value | ||
| Tissues | ||||
| Normal liver | 28 | 0.182±0.459 | 8.16 | <0.0001 |
| HCC | 171 | 5.001±2.453 | ||
| Age | ||||
| <60 | 66 | 4.405±2.513 | −2.563 | 0.011 |
| ≥60 | 106 | 5.376±2.349 | ||
| Sex | ||||
| Male | 114 | 5.457±2.393 | 3.556 | 0.0005 |
| Female | 57 | 4.089±2.332 | ||
| Race | ||||
| White | 84 | 5.077±2.379 | F=3.078 | 0.049 |
| Black | 11 | 6.522±1.740 | ||
| Yellow | 70 | 4.622±2.540 | ||
| T (tumor) | ||||
| T1+ T2 | 133 | 5.099±2.372 | 1.236 | 0.218 |
| T3+ T4 | 37 | 4.539±2.657 | ||
| Vascular invasion | ||||
| No | 95 | 4.898±2.405 | 0.521 | 0.603 |
| Yes | 51 | 5.118±2.509 | ||
| Patological grade | ||||
| g1+g2 | 107 | 5.068±.2.434 | 0.569 | 0.570 |
| g3+g4 | 61 | 4.847±2.382 | ||
| Stage | ||||
| I+ II | 126 | 5.065±2.333 | 1.544 | 0.125 |
| III +IV | 32 | 4.341±2.520 | ||
| Recurrence | ||||
| No | 151 | 4.942±2.468 | 1.334 | 0.184 |
| Yes | 10 | 6.008±2.029 | ||