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. 2017 Oct 16;51(6):1639–1650. doi: 10.3892/ijo.2017.4165

Figure 7.

Figure 7

High expression of E2F1 and DDR1 predicts worse survival in osteosarcoma. (A and B) The protein levels of E2F1 and DDR1 in osteosarcoma tissues were determined by western blotting. (C) Immunohistochemical staining of E2F1 and DDR1 in osteosarcoma tissues. Scale bar, 200 µm. (D) The correlation of concurrent immunostaining scores of E2F1 and DDR1 in osteosarcoma tissues. (E) OS curve of patients with osteosarcoma based on E2F1 expression. The cumulative 5-year survival rate of the patients with E2F1 high expressions was 28%, while that of the patients with E2F1 low expressions was 54.84%. (F) OS curve of patients with osteosarcoma based on DDR1 expression. The cumulative 5-year survival rate of the patients with DDR1 high expression was 31.11%, while that of the patients with DDR1 low expression was 47.22%.