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In vitro IC50 determination for 2,3-DHBA, 2,6-DHBA and 2,4,6-THBA using purified CDK1 enzyme and MTT assay in HCT-116 cells.
| Compounds | CDK1 IC50 (µM) | MTT assay HCT-116 (µM) 72 h |
|---|---|---|
| 2,3-DHBA | 386.1 | 1778.28 |
| 2,6-DHBA | 365.2 | 1949.84 |
| 2,4,6-THBA | 226.0 | 785.236 |
IC50 values for CDK1 inhibition in vitro and cytotoxicity assays in HCT-116 cell.
