Figure 5.

Effect of Scutellarin on xenografted MCF-7 tumor growth in nude mice. (A) Representative tumors from mice from Control, 5-U, Scutellarin and Combination groups. (B) Growth curve of MCF-7 tumors indicating means and the standard error. * P<0.05, ** P<0.01 vs. control. (C) Immunohistochemistry staining of p-YAP and YAP in xenografts tissue. Under the magnification ×200 microscope field, Expression levels of p-YAP were up-regulated in Scutellarin-treated and Combination groups, while YAP was lower in Scutellarin-treated groups than in the control. Bar, 100 μm.