Table 2.
Baseline characteristics of patients who did and did not achieve recovery at some point during follow-up
| Baseline characteristic | Recovery (n=668) |
No recovery (n=614) |
p-value |
|---|---|---|---|
| Age, mean (SD), years | 37.70 (10.07) | 38.25 (11.00) | 0.5710 |
| Gender, % | 0.0295 | ||
| Male | 40.9 | 46.9 | |
| Female | 59.1 | 53.1 | |
| Independent living, % | 0.8735 | ||
| Yes | 16.6 | 16.3 | |
| No | 83.4 | 83.7 | |
| Marital status, % | 0.0190 | ||
| Married, living together | 69.5 | 62.4 | |
| Never married | 11.7 | 12.9 | |
| Other | 18.9 | 24.8 | |
| Educational attainment, % | 0.0075 | ||
| ≤ Primary school | 6.3 | 9.4 | |
| Secondary school/occupational program | 42.1 | 46.7 | |
| ≥ University | 51.6 | 43.8 | |
| Employment status, % | 0.0664 | ||
| Full-time | 57.2 | 54.6 | |
| Economically inactive | 26.9 | 24.6 | |
| Unemployed/part-time | 15.9 | 20.8 | |
| Age at first episode of MDD, mean (SD), years | 34.45 (10.63) | 32.97 (11.82) | 0.0023 |
| Had MDD episode in last 24 months, % | 59.7 | 70.7 | <0.001 |
| Number of comorbidities (psychiatric and medical), % | <0.001 | ||
| None | 79.6 | 69.0 | |
| 1 | 18.2 | 21.3 | |
| >1 | 2.3 | 9.7 | |
| Painful physical symptoms, % | 49.6 | 55.5 | 0.0342 |
| Adherence (at visit 2–8 weeks), % | 77.3 | 57.4 | <0.001 |
| CGI-S, mean (SD) | 4.57 (0.70) | 4.51 (0.65) | 0.2304 |
| QIDS-SR16, mean (SD) | 14.43 (4.14) | 14.73 (4.81) | 0.4771 |
| SDS, mean (SD) | 17.20 (6.17) | 18.26 (6.46) | 0.0008 |
Note: Data are presented as percentage or mean (standard deviation) as appropriate.
Abbreviations: SD, standard deviation; MDD, major depressive disorder; CGI-S, Global Impressions of Severity; QIDS-SR16, 16-item Quick Inventory of Depressive Symptomatology Self-Report; SDS, Sheehan Disability Scale.