Table 3.
Baseline factors associated with recovery during follow-up
| Variables | Adjusted OR (95% CI)* | p-value |
|---|---|---|
| Higher QIDS-SR16 score | 1.00 (0.97–1.03) | 0.945 |
| Higher SDS score | 0.95 (0.93–0.97) | <0.001 |
| Being older | 1.00 (0.99–1.01) | 0.795 |
| Being male (vs female) | 1.01 (0.81–1.26) | 0.947 |
| Weeks (vs 8) | ||
| 16 | 3.88 (3.28–4.58) | <0.001 |
| 24 | 8.59 (7.07–10.45) | <0.001 |
| Educational attainment (vs ≥ university) | ||
| Secondary school/occupational program | 0.76 (0.61–0.95) | 0.016 |
| ≤ Primary school | 0.52 (0.33–0.83) | 0.006 |
| Having had MDD episodes in the past | 0.83 (0.66–1.04) | 0.107 |
| 24 months (vs not) | ||
| Having significant comorbidities at baseline | ||
| 1 | 0.70 (0.53–0.92) | 0.011 |
| >1 | 0.26 (0.14–0.48) | <0.001 |
| Having painful physical symptoms | 0.97 (0.78–1.21) | 0.776 |
| Being nonadherent to treatment at week 8 | 0.52 (0.41–0.67) | <0.001 |
Note:
*
This logistic regression model with repeated measures included recovery as a time-varying variable during follow-up and also adjusted for region and baseline treatment.
Abbreviations: OR, odds ratio; MDD, major depressive disorder; QIDS-SR16, 16-item Quick Inventory of Depressive Symptomatology Self-Report; SDS, Sheehan Disability Scale.