Table 1.

Frequent comorbidities in IBS seen in primary care

Comorbidity	Comments
Fibromyalgia	Most well-recognized and frequently encountered comorbidity in IBS patients;53,54 can be present in up to 33% of IBS patients.55
Chronic fatigue syndrome	Presence of chronic fatigue syndrome in IBS has been found to be about 14%.55
Chronic pelvic pain	Significant association with IBS reported in a large study;54 nearly 35% of women with IBS found to experience chronic pelvic pain.55
Temporomandibular joint disorder	A small study found that 16% of IBS patients had temporomandibular joint disorder.54
Major depression	Most frequent psychiatric comorbidity associated with IBS.55,56
Generalized anxiety disorder	Second-commonest psychiatric comorbidity seen in IBS patients.55,57

Abbreviation: IBS, irritable bowel syndrome.