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. Author manuscript; available in PMC: 2017 Dec 15.
Published in final edited form as: Cancer Res. 2017 Apr 20;77(12):3244–3254. doi: 10.1158/0008-5472.CAN-16-2355

Figure 1.

Figure 1

Effect of rubone monotherapy on miR-34a expression. A. miR-34a expression in prostate cancer and normal prostate cell lines (Student t test; **p < 0.01 vs. RWPE-1 cell, respectively, n = 3). B. Cytotoxicity of rubone on prostate cancer and normal prostate cell lines. C. Rubone upregulated miR-34a expression in DU145-TXR and PC3-TXR in a dose dependent manner (Student t test; **p < 0.01 vs. Rubone 0 μM, respectively, n = 3). Rubone alone reversed the expression of miR-34a downstream proteins in DU145 (D) and PC3 (E) cell lines.