Table 1.
Characteristics in 6179 critically-ill patients enrolled into the United States Critical Illness and Injury Trials Group Clinical Illness Outcomes Study.
| High number of protocols (≥ 19) | Low number of protocols (<19) | p-value | |
|---|---|---|---|
| Number of patients | 3116 | 3063 | |
| Median number of patients per ICU | 101 | 101 | |
| Age | 61.3 (17.4) | 57.8 (16.7) | 0.03 |
| Sex | 57% | 55% | 0.50 |
| Race | |||
| White (reference) | 79% | 61% | |
| Black | 16% | 29% | 0.02 |
| Other | 5% | 10% | 0.02 |
| Admission diagnosis | |||
| Cardiovascular only | 9% | 12% | 0.33 |
| Neurological only | 8% | 10% | 0.69 |
| Gastrointestinal only | 8% | 8% | 0.48 |
| Respiratory only | 12% | 15% | 0.14 |
| Infection only | 5% | 4% | 0.29 |
| Endocrine only | 1% | 2% | 0.34 |
| Trauma only | 3% | 3% | 0.56 |
| 2+ diagnoses (reference) | 41% | 39% | |
| Source of admission | |||
| Emergency Department (reference) | 46% | 43% | |
| Hospital Floor | 19% | 19% | 0.39 |
| Operating Room | 23% | 17% | 0.73 |
| Other Hospital | 12% | 14% | 0.57 |
| Other | 4% | 4% | 0.25 |
| Severity index | |||
| APACHE II, mean (SD) | 16.7 (7.0) | 16.6 (7.5) | 0.72 |
| SOFA, mean (SD) | 4.8 (3.6) | 4.9 (3.8) | 0.55 |
| Type of ICU | |||
| Surgical (reference) | 33% | 37% | |
| Medical | 49% | 37% | 0.45 |
| Mixed | 18% | 26% | 0.87 |
| Teaching status | |||
| Academic | 93% | 97% | 0.58 |
| Non-academic | 7% | 3% | |
| Annual number of hospital admissions | |||
| <25,000 (reference) | 19% | 30% | |
| 25,000 – 39,999 | 34% | 46% | 0.94 |
| ≥40,000 | 24% | 48% | 0.53 |