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. 2017 Nov 6;12(11):e0187698. doi: 10.1371/journal.pone.0187698

Fig 2. Increased sensitivity of VTA DA neurons to inhibition by DA during diestrus.

Fig 2

Extracellular recordings of VTA DA neurons were obtained from mice in diestrus and estrus. The DA response was measured in putative VTA DA neurons with 0.5, 1, 2, 5, and 10 μM DA. (A-B) Representative rate meter graphs show the effects of DA during (A) diestrus and (B) estrus. (C) Concentration-response graph showing enhanced inhibition to DA in mice during diestrus (n = 9) compared with estrus (n = 9). *P < 0.05 by two-way ANOVA.