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. 2017 Nov 6;12(11):e0187698. doi: 10.1371/journal.pone.0187698

Fig 3. Increased sensitivity of VTA DA neurons to ethanol excitation during diestrus.

Fig 3

Extracellular recordings of VTA DA neurons were obtained from mice in diestrus and estrus. The ethanol response was measured in VTA DA neurons with 40, 80, and 120 mM ethanol. Representative rate meter graphs show the effects of ethanol during (A) diestrus and (B) estrus. (C) Pooled concentration-response graph showing excitation by ethanol in mice during diestrus (n = 9) compared with estrus (n = 7). **P < 0.01 by two-way ANOVA.