Table 4. Demographic data and clinical characteristics of infants with and without AKI.
No AKI, n = 122 | AKI, n = 154 | p value | |
---|---|---|---|
Infants’ demographic data | |||
Gestational age (weeks)* | 27 (26,28) | 25 (24,26) | <0.001 |
Birth weight* | 847 (741,915) | 745 (662,832) | <0.001 |
Male gender | 56 (46%) | 88 (57%) | 0.063 |
Cesarean section | 98 (80%) | 104 (68%) | 0.015 |
Multiple birth | 27 (22%) | 43 (28%) | 0.272 |
Apgar score at 1 minute* | 5 (4,7) | 4 (3,5) | <0.001 |
Apgar score at 5 minutes* | 8 (7,9) | 7 (6,8) | <0.001 |
1st arterial blood gas pH* | 7.33 (7.27,7.39) | 7.28 (7.18,7.36) | <0.001 |
Clinical intervention | |||
Umbilical artery catheter | 82 (67%) | 121 (79%) | 0.034 |
High frequency ventilator | 51 (42%) | 125 (81%) | <0.001 |
Gentamicin | 88 (72%) | 96 (62%) | 0.087 |
NSAIDs | 7 (6%) | 15 (10%) | 0.223 |
Inotropic agents | 66 (54%) | 132 (86%) | <0.001 |
Co-morbidity | |||
Culture-proven bacteremia/fungemia | 24 (20%) | 34 (22%) | 0.626 |
Intraventricular hemorrhage | 25 (21%) | 62 (40%) | 0.001 |
Necrotizing enterocolitis, stage II/III | 10 (8%) | 6 (4%) | 0.129 |
Patent ductus arteriosus | 44 (36%) | 118 (77%) | <0.001 |
Maternal clinical exposure | |||
Diabetes | 7 (6%) | 2 (1%) | 0.047 |
Hypertension | 12 (10%) | 6 (4%) | 0.047 |
Pre-eclampsia | 31 (25%) | 11 (7%) | <0.001 |
Chorioamnionitis | 10 (8%) | 27 (18%) | 0.024 |
Prenatal antibiotics | 52 (43%) | 85 (55%) | 0.038 |
Prenatal steroids | 83 (68%) | 93 (60%) | 0.190 |
Placental hemorrhage | 10 (8%) | 21 (14%) | 0.155 |
Premature rupture of membranes | 43 (35%) | 51 (33%) | 0.711 |
*presented as the median and interquartile range.