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. 2017 Nov 6;12(11):e0187764. doi: 10.1371/journal.pone.0187764

Table 4. Demographic data and clinical characteristics of infants with and without AKI.

No AKI, n = 122 AKI, n = 154 p value
Infants’ demographic data
    Gestational age (weeks)* 27 (26,28) 25 (24,26) <0.001
    Birth weight* 847 (741,915) 745 (662,832) <0.001
    Male gender 56 (46%) 88 (57%) 0.063
    Cesarean section 98 (80%) 104 (68%) 0.015
    Multiple birth 27 (22%) 43 (28%) 0.272
    Apgar score at 1 minute* 5 (4,7) 4 (3,5) <0.001
    Apgar score at 5 minutes* 8 (7,9) 7 (6,8) <0.001
    1st arterial blood gas pH* 7.33 (7.27,7.39) 7.28 (7.18,7.36) <0.001
Clinical intervention
    Umbilical artery catheter 82 (67%) 121 (79%) 0.034
    High frequency ventilator 51 (42%) 125 (81%) <0.001
    Gentamicin 88 (72%) 96 (62%) 0.087
    NSAIDs 7 (6%) 15 (10%) 0.223
    Inotropic agents 66 (54%) 132 (86%) <0.001
Co-morbidity
    Culture-proven bacteremia/fungemia 24 (20%) 34 (22%) 0.626
    Intraventricular hemorrhage 25 (21%) 62 (40%) 0.001
    Necrotizing enterocolitis, stage II/III 10 (8%) 6 (4%) 0.129
    Patent ductus arteriosus 44 (36%) 118 (77%) <0.001
Maternal clinical exposure
    Diabetes 7 (6%) 2 (1%) 0.047
    Hypertension 12 (10%) 6 (4%) 0.047
    Pre-eclampsia 31 (25%) 11 (7%) <0.001
    Chorioamnionitis 10 (8%) 27 (18%) 0.024
    Prenatal antibiotics 52 (43%) 85 (55%) 0.038
    Prenatal steroids 83 (68%) 93 (60%) 0.190
    Placental hemorrhage 10 (8%) 21 (14%) 0.155
    Premature rupture of membranes 43 (35%) 51 (33%) 0.711

*presented as the median and interquartile range.