Table 3. Consistency of gene-electrophysiological property correlations between NeuroExpresso/NeuroElectro discovery and AIBS validation datasets.

Overall AIBS consistency indicates overall Spearman rank correlation between the full set of gene-electrophysiological correlations calculated in both the discovery and validation datasets, as shown in Fig 2B. P-values based on 1000 random reshuffles of cell type labels in the AIBS validation dataset. Discovered genes, p_adj < 0.05 reflects count of genes significantly correlated with each ephys property with in discovery dataset (only includes genes that are also present in AIBS scRNAseq dataset). AIBS consistency, |r_s|> 0.3 reflects count and percentage of discovered genes that further show a consistent relationship in the AIBS validation dataset. P-value also based on 1000 shuffled samples of cell type labels in the validation dataset.

Ephys Property	Overall AIBS consistency		Discovered genes; padj < 0.05	AIBS consistency; |rs| > 0.3
	Spearman corr.	p-value	count	count	%	p-value
AHPamp	0.45	0.009	285	204	72	0.005
APamp	0.404	<0.001	169	119	70	0.006
APhw	0.04	0.323	4	3	75	0.056
APthr	-0.146	0.877	0	---	---	---
Cm	0.384	0.037	80	55	69	0.015
FRmax	0.209	0.074	21	7	33	0.159
Rheo	-0.049	0.649	15	5	33	0.162
Rin	0.346	0.004	144	68	47	0.029
SFA	0.298	0.01	2	1	50	0.277
Tau	-0.106	0.713	6	5	83	0.007
Vrest	0.332	0.029	279	148	53	0.025