Table 4.
Grades 3, 4, and 5 Maximal Adverse Events at Least Possibly Related to Treatment
| Age Groups | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Aged <70 Years Group | Aged ≥70 Years Group | ||||||||||
| Grade | Grade | ||||||||||
| 3 | 4 | 3 | 4 | 5 | |||||||
| Body system | Toxicity | No. | % | No. | % | No. | % | No. | % | No. | % |
| Hematology | Anemia | 4 | 14 | 1 | 3 | 1 | 6 | ||||
| Leukopenia | 3 | 10 | |||||||||
| Lymphopenia | 2 | 7 | |||||||||
| Neutropenia | 7 | 24 | 6 | 21 | 4 | 24 | 3 | 18 | |||
| Thrombocytopenia | 1 | 3 | 7 | 24 | 1 | 6 | 2 | 12 | |||
| Hemorrhage | Colonic hemorrhage | 1 | 3 | ||||||||
| Hepatic | Bilirubin | 1 | 6 | ||||||||
| Infection/Febrile neutropenia | Blood Infection | 1 | 6 | ||||||||
| Metabolic/laboratory | Hyperglycemia | 3 | 10 | ||||||||
| Hyponatremia | 1 | 3 | 1 | 6 | |||||||
| Alk Phosphatase | 1 | 3 | |||||||||
| Neurology | Dizziness | 2 | 7 | ||||||||
| Syncope | 1 | 3 | |||||||||
| Pulmonary | Dyspnea | 1 | 3 | ||||||||
| Constitutional symptoms | Fatigue | 3 | 10 | 2 | 12 | ||||||
| Gastrointestinal | Anorexia | 2 | 7 | 1 | 6 | ||||||
| Diarrhea | 1 | 3 | |||||||||
| Pancreatitis | 1 | 6 | |||||||||