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editorial
. 2017 Aug 2;1(6):473–476. doi: 10.1002/hep4.1067

Figure 1.

Figure 1

Schematic overview of the role of Rab7 and dynamin2 (Dyn2) in ethanol‐impaired lipophagy. Chronic ethanol exposure reduces Rab7 and Src/Dyn2 activity and thus may inhibit the docking of LDs to the autophagosome and impair ALR and lysosome biogenesis, respectively resulting in impaired lipophagy and promoting hepatic steatosis. Abbreviation: P, phosphorylation.