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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Andrology. 2017 Aug 22;5(6):1141–1152. doi: 10.1111/andr.12409

Figure 3.

Figure 3

p53−/− rats have reduced seminiferous tubule diameter and spermatid release, relative to p53+/+. Representative images of stage VII/VIII seminiferous tubules in a p53+/+ testis (A) and a p53−/− testis (B), showing reduced numbers of elongate spermatids releasing in p53−/− testes. Representative minor axis seminiferous tubule diameters measure 292.2 μm and 265.4 μm, respectively. Scale bar = 100 μm. Seminiferous tubule diameter was measured for 51–73 tubules (mean = 57.3 tubules) on H&E-stained left testis sections. The average tubule diameter (mean ± SEM) is lower in p53−/− testes than p53+/+, including both atrophic and normal p53−/− samples (C). **p < 0.01 by t-test (n = 5 rats).