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Baicalin evidently inhibits the Mtb-induced NLRP3 inflammasome activation. (A) Levels of NLRP3, ASC and pro-caspase-1 expression in cell lysates and the mature IL-1β in the supernatant were determined by immunoblot. (B) ASC or NLRP3 immunoprecipitates from Raw264.7 cells were immunoblotted for NLRP3 or ASC respectively, and re-blotted for ASC or NLRP3 respectively. Experiment performed three times.
