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. 2017 Nov 2;8:2142. doi: 10.3389/fmicb.2017.02142

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Copyright © 2017 Zhang, Sun, Wang, He, Wang, Zheng, Wu, Zhang and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bacalin suppresses the PI3K/Akt/mTOR pathway but has no effect on the MAPK signaling in Raw264.7 cells. (A) Western blot analysis of mTOR, p-mTOR, Akt, and p-Akt expression in Raw264.7 cells. β-actin was used as a control. The right bar graphs show the statistical results for the relative quantitative expression of p-Akt and p-mTOR. (B) Western blot analysis of p-JNK, p-ERK, and p-p38 expression in Raw264.7 cells. The right and below bar graphs show the statistical results for the relative quantitative expression of p-p38, p-ERK, and p-JNK. Data are shown with the means ± SD of at least three independent experiments. ^*p < 0.05.