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. 2017 Nov 2;9:359. doi: 10.3389/fnagi.2017.00359

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Copyright © 2017 Wang, Mu, Lin, Geng, Xiao, Zhang, Wang, Guan and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Curly vessels in the brain of SHR increased significantly than SD rats. Angiography pictures were presented from SHR (A,C,E) and SD (B,D,F) rats in 3-, 9-, and 12-month. The images in square frames of graphs (a–f) were amplified as images (A–F), respectively. Square frame defines the selected area for calculating. Arrowhead points to curly vessels. Scale bar = 1 mm.