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In vivo FMSN-PEG-UEA1 -guided confocal laser endomicroscopy. AOM/DSS treated (a, c) and control (b, d) mice were insufflated and irrigated via enema with FMSN-PEG-UEA1 for 3 minutes prior to evacuation and saline irrigation, to reduce unbound nanoparticle background fluorescence. Images were obtained by white light colonoscopy (a, b) and probe-based laser confocal fluorescence endomicroscopy (c, d). Scale bar: 20 µm.
