Table 1.

Results of the ChemRICH enrichment analysis for the altered metabolites in the NOD mice study. Abbreviations - PC: Phosphatidylcholines, LPC: Lysophosphatidylcholines, BCAA: Branched chains amino acids, TG: Triacylglycerols, PI: Phosphatidylinositol, PE: Phosphatidylethanolamine.

Cluster name	Cluster size	p-values	FDR	Counts of altered	Increased	Decreased
Unsaturated_LPC	9	2.2E-20	1.1E-18	9	0	9
Unsaturated_TG	46	1.5E-15	3.7E-14	31	30	1
PC	44	5E-13	8.2E-12	29	1	28
Saturated_LPC	3	2.7E-12	3.4E-11	3	0	3
BCAA	3	5.8E-12	5.7E-11	3	3	0
Saturated_TG	4	1.6E-11	1.3E-10	4	4	0
butyrates	3	6.1E-10	4.3E-09	3	2	1
sphingomyelins	16	1.1E-09	6.8E-09	13	1	12
hexoses	9	0.0000022	0.000012	7	6	1
pentoses	3	0.0000041	0.000018	3	3	0
plasmalogens	3	0.0000041	0.000018	3	0	3
disaccharides	7	0.0000071	0.000029	6	6	0
hydroxybutyrates	3	0.000011	0.00004	3	3	0
PI	6	0.000022	0.000076	5	0	5
sugar acids	9	0.00014	0.00046	6	6	0
cholesterol esters	4	0.00051	0.0016	3	0	3
DiHODE	4	0.001	0.003	2	0	2
PE	9	0.0023	0.0063	5	1	4
indoles	3	0.016	0.04	2	2	0
amino acids, aromatic	3	0.02	0.048	2	0	2
sugar alcohols	9	0.022	0.051	4	3	1
Saturated FA	9	0.027	0.057	3	2	1
HETrE	3	0.027	0.057	2	0	2
HETE	6	0.028	0.057	3	0	3
oxo-ETE	4	0.03	0.058	2	0	2
amino acids, sulfur	4	0.038	0.07	2	0	2
pyridines	3	0.039	0.07	2	2	0
hexosephosphates	3	0.04	0.07	2	2	0
tricarboxylic acids	3	0.041	0.07	2	2	0