Table 3.
Characteristics | Active LN | Healthy Controls | P-value |
---|---|---|---|
Number | 20 | 20 | NA |
Sex (F/M) | 19/1 | 19/1 | NA |
Age (average, s.d.) | 33.75, 8.52 | 38.3, 8.93 | 0.1518 |
Clinical parameters (average, s.d.) | |||
Serum creatinine (mg/dL) | 1.002, 0.1065 | NA | NA |
Proteinuria (g/day) | 3.081, 0.3996 | NA | NA |
Urinary Erythrocyte Count (/HPF) | 10.55, 4.863 | NA | NA |
MDRDa GFR (mL/min) | 82.08, 7.259 | NA | NA |
LN Renal Histology | |||
Class III | 1/20 | NA | NA |
Class IV | 11/20 | NA | NA |
Class V | 2/20 | NA | NA |
Class III + V | 1/20 | NA | NA |
Class IV + V | 5/20 | NA | NA |
Activity index (average, s.d.) | 5.9, 3.63 | NA | NA |
Chronicity index (average, s.d.) | 5.2 ± 3.85 | NA | NA |
Steroid dose (mg/day) (average, s.d.) | 19.63 ± 2.829 | NA | NA |
F, female; M, male; NA, not available; s.d., standard deviation; GFR, glomerular filtration rate; MDRD, The Modification of Diet in Renal Disease; HPF, high power field; LN, Lupus nephritis.
aThe equation to calculate estimate glomerular filtration rate for Thais is 375.5 × serum Creatinine (−0.848) × age (−0.364) × 0.712 (if female).