Table 3.
Growth inhibitory in vitro activity of FMDP-oligopeptides against C. albicans wild type cells and oligopeptide transporters-deficient mutants, determined in YNB-SG medium.
| Strain | SC 5314 | opt1Δ | opt2Δ opt3Δ | opt4Δ | opt5Δ | opt1–opt5Δ | ptr2Δ ptr22Δ | opt1–opt5Δ ptr2Δ ptr22Δ |
|---|---|---|---|---|---|---|---|---|
| Peptide | MIC (μg mL-1) | |||||||
| F2 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.125 | >128 | >128 |
| F3 | 0.25 | 0.5 | 0.25 | 0.25 | 0.25 | 0.25 | >128 | >128 |
| F6 | 0.5 | 4 | 32 | 8 | 4 | 64 | 0.5 | 64 |
| F7 | 0.5 | 8 | 32 | 16 | 2 | 64 | 0.5 | 64 |
| P10 | 64 | 64 | 64 | 64 | 64 | 64 | 64 | 64 |
| F11 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 | 0.125 | >128 | >128 |