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. 2017 Aug 17;117(8):1164–1175. doi: 10.1038/bjc.2017.260

Figure 2.

Figure 2

COMMD10 inhibits the proliferation, invasion and metastasis of CRC cells. (A) Effects of COMMD10 overexpression and knockdown on CRC cell proliferation in vitro. (B) Effect of COMMD10 overexpression and knockdownon on plate colony formation of CRC cells. *P<0.001. (C) Effects of COMMD10 overexpression and knockdown on CRC cell invasion in vitro by Boyden chamber. Scale bars represented 50 μm. *P<0.001. (D) Effect of COMMD10 knockdown on subcutaneous tumour growth in vivo. **P<0.001. (E) Effect of COMMD10 knockdown on lung metastasis in nude mice. Error bars represent mean±s.d. from three independent experiments. Scale bars represent 50 μm. *P=0.033. A full colour version of this figure is available at the British Journal of Cancer journal online.