Fig. 1. PQS signaling in P. aeruginosa. Genes involved in virulence production and regulation at a transcriptional level are highlighted in ‘Box A’ on the right. For a full list of genes under PqsR (also known as MvfR) transcriptional regulation see article by Déziel et al. 25 HHQ also binds PqsR albeit with a 100-fold lower potency than PQS.20 (–) Represents down-regulation (+) represents positive regulation.
