FIG 6.

Immunization with MSP-1D eliciting opsonizing antibodies in rhesus macaques. Rhesus monkeys (n = 5) were immunized three times (days 0, 28, and 56) with recombinant MSP-1D and adjuvant (CoVaccine HT). Blood was sampled on days 0, 70, and 182. The ADRB activity of protein G-purified IgG from blood was analyzed against P. falciparum 3d7 (A) and FCB1 (B) merozoites. d0, preimmune control IgG; Nouna IgG Pool, protein G-purified IgG from 11 semi-immune individuals from Nouna, Burkina Faso. Statistical differences were assessed by one-way repeated-measures ANOVA. **, P ≤ 0.01.