Table 4. . MAPK inhibitors.

No.	Structure	Inhibitor class	Publication year	Activity
37		Synthetic (SB 203580)	1996	IC50 = 0.3–0.5 µM
38		Synthetic (SB 220025)	1998	IC50 = 60 nM
39		Synthetic (RWJ 67657)	1999	p38α (IC50 = 1 μM) p38β (IC50 = 11 μM)
40		Synthetic (VX-702)	2007	p38α (IC50 = 4–20 nM)
41		Synthetic (Scio-469)	2006	p38α (IC50 = 9 nM)
42		Synthetic Dilmapimod (SB681323)	2005	Under study in early phase
43		Synthetic	2007	IC50 = 3 nM
44		Synthetic	2007	IC50 = 3 nM
45		BMS582949	2006–2015	p38α (IC50 = 13 nM)
46		Synthetic (VX-745)	1999	p38α (IC50 = 5 nM)