Table 5. . Inhibitors of glycogen synthase kinase-3β.
No. | Structure | Inhibitor class | Publication year | Activity |
---|---|---|---|---|
47 | Natural (hymenialdisine) | 2000 | IC50 = 0.01 µM | |
48 | Natural (5-iodo-indirubin-3'-monoxime) | 2001 | IC50 = 0.009 nM | |
49 | Synthetic (alesterpaullone) | 2000 | IC50 = 0.004 nM | |
50 | Synthetic (aloisine A) | 2002 | IC50 = 0.65 µM | |
51 | Synthetic | 2003 | IC50 = 0.018 µM |