Fig. 7.
TAGLN2 silencing inhibited tumorigenesis in vivo. a H&E staining of sections from mouse brains with U87MG control or sh-TAGLN2 xenografts at ~ 4 weeks after implantation with 1 × 106 cells, and (b) tumor size (mm3) was measured. c H&E staining of sections at tumor margins in intracranial U251 control or sh-TAGLN2 xenografts. d Survival analysis for animals implanted with U87MG sh-TAGLN2 or control cells (P < 0.05 by log-rank test; n = 5 animals per group) (e) IHC for TAGLN2, N-cadherin and Ki-67 in sections from indicated xenografts. Magnification: ×200