Table 3. Multivariate survival analysis.
Variables | Coefficient | 95% confidence interval | P value | |
---|---|---|---|---|
Lower | Upper | |||
Treatment | ||||
Surgery | Reference | |||
Neoadjuvant | 0.60 | 0.53 | 0.68 | <0.001 |
Adjuvant | 0.52 | 0.48 | 0.56 | <0.001 |
Age (years) | ||||
18–59 | Reference | |||
60–69 | 1.12 | 1.00 | 1.25 | 0.043 |
70–79 | 1.23 | 1.08 | 1.40 | 0.001 |
80–90 | 1.35 | 1.15 | 1.59 | <0.001 |
Sex | ||||
Male | Reference | |||
Female | 0.96 | 0.89 | 1.04 | 0.309 |
Race | ||||
White | Reference | |||
Black | 0.89 | 0.83 | 1.37 | 0.606 |
Other | 0.89 | 0.79 | 0.99 | 0.033 |
Hispanic | 1.00 | 0.80 | 1.00 | 0.050 |
Insurance | ||||
Medicare | Reference | |||
Private | 0.91 | 0.82 | 1.01 | 0.065 |
Medicaid & other gov | 1.01 | 0.86 | 1.20 | 0.866 |
Unknown | 0.40 | 0.29 | 0.55 | <0.001 |
Not Insured | 1.07 | 0.83 | 1.37 | 0.606 |
Median income | ||||
<58,000 | Reference | |||
58,000–74,000 | 0.88 | 0.79 | 0.99 | 0.033 |
74,000–93,000 | 0.89 | 0.80 | 1.00 | 0.050 |
>93,000 | 0.81 | 0.72 | 0.91 | <0.001 |
Comorbidities | ||||
CDCC score 0 | Reference | |||
CDCC score 1 | 1.03 | 0.95 | 1.12 | 0.462 |
CDCC score 2 | 1.24 | 1.08 | 1.43 | 0.002 |
Facility type | ||||
Community | Reference | |||
Comprehensive community | 0.91 | 0.75 | 1.09 | 0.301 |
Academic/research | 0.79 | 0.65 | 0.95 | 0.013 |
Other | 1.54 | 0.75 | 3.18 | 0.243 |
Facility location | ||||
Northeast | Reference | |||
South | 1.04 | 0.93 | 1.16 | 0.501 |
Midwest | 1.12 | 1.00 | 1.25 | 0.046 |
West | 0.87 | 0.76 | 0.99 | 0.036 |
Surgery type | ||||
Distal resection | Reference | |||
Whipple | 1.17 | 1.04 | 1.32 | 0.010 |
Total resection | 1.10 | 0.95 | 1.28 | 0.203 |
Other | 1.10 | 0.96 | 1.26 | 0.171 |
Surgical margins | ||||
No residual tumor | Reference | |||
Residual tumor, NOS | 1.57 | 1.39 | 1.78 | <0.001 |
Microscopic residual tumor | 1.62 | 1.46 | 1.80 | <0.001 |
Macroscopic residual tumor | 1.50 | 1.06 | 2.11 | 0.021 |
Indeterminate or unknown | 1.16 | 0.94 | 1.43 | 0.177 |
Pathological stage | ||||
Stage 0 | Reference | |||
Stage 1 | 0.66 | 0.51 | 0.86 | 0.002 |
Stage 2 | 1.08 | 0.86 | 1.35 | 0.521 |
Stage 3 | 1.24 | 0.92 | 1.66 | 0.153 |
Stage 4 | 1.91 | 1.37 | 2.68 | <0.001 |
Unknown | 1.08 | 0.83 | 1.41 | 0.556 |
CA 19-9 (U/mL) | ||||
≤100 | Reference | |||
101–300 | 1.10 | 0.95 | 1.27 | 0.184 |
301–500 | 1.08 | 0.90 | 1.29 | 0.393 |
501–800 | 1.08 | 0.91 | 1.28 | 0.409 |
801–980 | 3.29 | 2.89 | 3.74 | <0.001 |
>980 | 1.51 | 1.36 | 1.69 | <0.001 |
NOS, not otherwise specified.