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Flow diagram of patient recruitment to this study. During the study period, 2,749 patients were admitted to the intensive care unit (ICU) and 102 were excluded due to age (<18 years). One hundred patients with systematic inflammatory response syndrome (SIRS) whose predicted length of stay (LOS) in the ICU was >4 days were enrolled. Ninety five patients had a Sequential Organ Failure Assessment (SOFA) score ≥2. After exclusion of three ineligible patients, 92 patients were analyzed.
