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Schematic diagram of NO synthesis and action on ischemic stroke and hemorrhagic stroke.
Note: NO: Nitric oxide; NOS: nitric oxide synthase; nNOS: neuronal NOS; eNOS: endothelial NOS; iNOS: inducible NOS; sGC: soluble guanylate cyclase; ROS: reactive oxygen species; DIND: delayed ischemic neurological deficits; onoo-: peroxynitrite anion; NF-κB: nuclear factor-κB; GTP: guanosine triphosphate; cGMP: cyclic guanosine monophosphate.
