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. 2017 Oct 24;2017:2583910. doi: 10.1155/2017/2583910

Figure 1.

Figure 1

Apomorphine- (APO-) induced rotational behaviour in Parkinson's disease (PD) model rats. The striatal dopamine receptors can be super-sensitized due to a marked decrease in striatal dopamine concentration by 6-OHDA injection. Therefore, apomorphine, which is a dopamine receptor agonist, injected into the peripheral tissues, can induce the rats to exhibit rotational behaviour to the left.