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. Author manuscript; available in PMC: 2017 Nov 7.
Published in final edited form as: Cell Metab. 2014 Dec 2;20(6):979–990. doi: 10.1016/j.cmet.2014.11.004

Figure 1. Increased β Cell Mass and Insulin Content in Nonpregnant Pdx1-CreLate Mice.

Figure 1

(A and B) Blood glucose levels in random-fed (A) and fasted (B) Pdx1-CreLate versus control mice. Data are represented as mean ± SEM, n = 7 mice per genotype, **p < 0.01.

(C) Insulin tolerance test (ITT) on 10-week-old Pdx1-CreLate versus control mice. Values are presented as a percentage compared to the starting glucose level. Data are represented as mean ± SEM, n = 7–8 mice per genotype.

(D) Quantification of β cell mass in 24-week-old Pdx1-CreLate versus control mice, performed as described in the Experimental Procedures. Data are represented as mean ± SEM, n = 4 mice per genotype, **p < 0.01.

(E) Pancreatic insulin content in 24-week-old Pdx1-CreLate versus control mice. Data are represented as mean ± SEM, n = 9–10 mice per genotype, **p < 0.01.