Table 5.
Prevalence of Systemic Autoimmunity Among Patients’ Individual Family Members
| Patient Subgroup | Relatives, No. With Systemic Autoimmunity/Total No. (%)
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Mothers | Fathers | Sisters | Brothers | Grand-mothers | Grand-fathers | Aunts | Uncles | |
| All WSS | 18/69 (26) | 6/48 (12) | 13/91 (14) | 9/101 (9) | 7/34 (21) | 1/18 (6) | 12/129 (9) | 6/119 (5) |
| MFC/PIC, AZOOR, or birdshot chorioretinopathy only (n = 854) | 16/53 (30) | 6/38 (16) | 12/69 (17) | 8/84 (10) | 7/27 (26) | 1/12 (8) | 10/97 (10) | 5/92 (5) |
| MFC/PIC (n = 557) | 9/33 (27) | 5/29 (17) | 7/38 (18) | 6/45 (13) | 6/22 (27) | 1/9 (11) | 8/73 (11) | 1/61 (2) |
| AZOOR (n = 163) | 4/11 (36) | 1/4 (25) | 1/17 (6) | 2/25 (8) | 0/1 | NA | 1/14 (7) | 2/20 (10) |
| Birdshot chorioretinopathy (n = 134) | 3/9 (33) | 0/5 | 4/14 (29) | 0/14 | 1/4 (25) | 0/9 | 1/10 (10) | 2/11 (18) |
| MEWDS (n = 128) | 1/8 (12) | 0/5 | 1/15 (7) | 1/5 (20) | 0/4 | 0/6 | 2/22 (9) | 1/13 (8) |
| APMPPE (n = 48) | 0/3 | 0/3 | 0/2 | 0/6 | 0/2 | 0/1 | 0/3 | 0/7 |
| Serpiginous choroiditis (n = 37) | 1/3 (33) | 0/1 | 0/4 | 0/3 | 0/1 | 0/1 | 0/4 | 0/4 |
Abbreviations: APMPPE, acute posterior multifocal placoid pigment epitheliopathy; AZOOR, acute zonal occult outer retinopathy; MEWDS, multiple evanescent white dot syndrome; MFC/PIC, multifocal choroiditis/punctate inner choroidopathy; NA, not applicable; WSS, white spot syndromes.