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. Author manuscript; available in PMC: 2017 Nov 7.
Published in final edited form as: Arch Ophthalmol. 2009 Jul;127(7):869–874. doi: 10.1001/archophthalmol.2009.132

Table 6.

Prevalence of Systemic Autoimmunity Among Stated Categories

Patient Subgroup Relatives, No. With Systemic Autoimmunity/Total No. (%)
First-Degree Relatives Second-Degree Relatives Female Relatives Male Relatives Maternal Relatives Paternal Relatives
All WSS 57/450 (13) 49/646 (8) 73/578 (13) 33/519 (6) 31/380 (8) 18/266 (7)
MFC/PIC, AZOOR, or birdshot chorioretinopathy only (n = 854) 51/361 (14) 43/493 (9) 65/450 (14) 29/404 (7) 27/292 (9) 16/201 (8)
MFC/PIC (n = 557) 30/211 (14) 30/346 (9) 42/299 (14) 18/258 (7) 16/192 (8) 14/154 (9)
AZOOR (n = 163)   12/85 (14)       8/78 (10) NA NA NA NA
Birdshot chorioretinopathy (n = 134)     9/65 (14)     5/69 (7)   11/73 (15)     3/61 (5)     4/51 (8)     1/18 (6)
MEWDS (n = 128)     4/42 (10)     5/86 (6)   5/80 (6)     4/48 (8)     3/50 (6)     2/36 (6)
APMPPE (n = 48) 0/15 0/33 0/20 0/29 0/14 0/19
Serpiginous choroiditis (n = 37)     1/20 (5) 0/17   1/18 (6) 0/19 0/11 0/6

Abbreviations: APMPPE, acute posterior multifocal placoid pigment epitheliopathy; AZOOR, acute zonal occult outer retinopathy; MEWDS, multiple evanescent white dot syndrome; MFC/PIC, multifocal choroiditis/punctate inner choroidopathy; NA, not applicable; WSS, white spot syndromes.