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. Author manuscript; available in PMC: 2017 Nov 27.
Published in final edited form as: Science. 2017 Oct 27;358(6362):446–447. doi: 10.1126/science.aaq0143

Figure 2. Surface sensing and attachment by Caulobacter crescentus.

Figure 2

When a free-swimming Caulobacter bacterium encounters a surface, either the intact flagellar motor, acting as a mechanosensitive channel, or a pilus, inhibited from retraction upon surface contact, stimulates localized c-di-GMP production that results in holdfast production and surface adherence. For the flagellum, the DgcB protein is responsible for c-di-GMP production at the cell pole, which binds to the HfsJ component of the holdfast synthesis machinery.