Table 2.
Correspondence of the 18 convergence candidate regions (CCR) identified as putative selection signals for Churra and Australian Merino sheep populations with previously reported signatures of selection
| Present study | Other studies | |||
|---|---|---|---|---|
| Region | Genomic interval (Mb) | Correspondence with other studies Chr: peak marker/interval (Mb) |
Putative candidate genes according to other studies | Population (target trait) |
| CCR1 | Chr2: 51.659–53.837 | OAR2: 52.266–52.454 | Zel-Lori Bakhtiri and HapMap dataset [25] (fat deposition) | |
| OAR2: 52.40 (peak SNP) | HapMap dataset [21] | |||
| OAR2: 51.41–53.44 | HapMap dataset [22] | |||
| OAR2: 51.72–51.95 | HapMap dataset [28] (climate adaptation) | |||
| OAR2: 51.200–52.100; 52.100–52.900; 53.60–54.5800 | Duolang sheep [27] (ecoregion adaptation) | |||
| CCR2 | Chr2: 78.854–79.190 | |||
| CCR3 | Chr3: 151.088–152.393 | OAR3: 150.5–154.2 | HMGA2, WIF1 | Spanish breeds [30] |
| OAR3: 151.42–156.93 | HMGA2 | HapMap dataset [22] | ||
| OAR3: 152.68–154.679 | HapMap dataset [19] (dairy specialization) | |||
| CCR4 | Chr3: 152.545–153.519 | OAR3: 150.5–154.2 | HMGA2, WIF1 | Spanish breeds [30] |
| OAR3: 152.68–154.679 | HapMap dataset [19] (dairy specialization) | |||
| CCR5 | Chr3: 154.007–154.523 | OAR3: 154.213 (peak SNP) | HMGA2, MSRB3, LEMD3 | HapMap dataset [21] |
| OAR3: 154.79–154.93 | HapMap dataset [22] | |||
| OAR3: 151.42–156.93 | HapMap dataset [22] | |||
| OAR3: 150.5–154.2 | Spanish breeds [30] | |||
| OAR3: 152.68–154.679 | HapMap dataset [19] (dairy specialization) | |||
| CCR6 | Chr3: 154.638–158.339 | OAR3: 154.79–154.93 | HapMap dataset [22] | |
| CCR7 | Chr3: 179.816–180.129 | |||
| CCR8 | Chr3: 182.779–182.916 | OAR3: 182.00–184.00 | Duolang sheep [27] (ecoregion adaptation) | |
| CCR9 | Chr3: 183.347–183.430 | OAR3: 182.00–184.00 | Duolang sheep [27] (ecoregion adaptation) | |
| CCR10 | Chr3: 187.634–188.482 | |||
| CCR11 | Chr6: 36.461–36.914 | OAR6: 36.073 (peak SNP) | ABCG2, NCAPG, PDK2 | HapMap dataset [21] |
| OAR6: 34.71–39.12 | HapMap dataset [22] | |||
| OAR6: 36.63–36.8 | HapMap dataset [28] (climate adaptation) | |||
| OAR6: 36.200–36.500 | Duolang sheep [27] (ecoregion adaptation | |||
| OAR6: 30.367–41.863 | HapMap dataset [19] (dairy specialization) | |||
| CCR12 | Chr6: 37.164–38.580 | OAR6: 34.71–39.12 | ||
| OAR6: 37.2–38.0 | HapMap dataset [22] | |||
| OAR6: 37.40–37.60 | HapMap dataset [24] | |||
| LCORL, NCAPG | Small-tailed Han sheep [27] (ecoregion adaptation) | |||
| OAR6: 30.367–41.863 | HapMap dataset [19] (dairy specialization) | |||
| CCR13 | Chr8: 32.779–33.477 | OAR8: 32.159 (Peak SNP) | BVES | HapMap dataset [21] |
| CCR14 | Chr8: 37.075–37.423 | |||
| CCR15 | Chr10: 29.344–29.713 | OAR10: 29.476 (peak SNP) | RXFP2 | HapMap dataset [21] |
| OAR10: 29.1–29.3 | Spanish breeds [30] | |||
| OAR10: 28.50–30.50 | HapMap dataset [22] | |||
| OAR10: 28.71–29.00 | HapMap dataset [28] (climate adaptation) | |||
| HapMap dataset [24] | ||||
| HapMap dataset [24] | ||||
| OAR10: 27.1–31.2 | Small-tailed Han sheep [27] (ecoregion adaptation | |||
| OAR10: 29.1–31.9 | RXFP2, B3GALTL | Duolang sheep [27] (ecoregion adaptation) | ||
| OAR10: 29.40–29.700 | ||||
| OAR10: 29.50–29.400 | ||||
| CCR16 | Chr11: 26.512–26.940 | OAR11: 24.18–38.74 | HapMap dataset [22] | |
| OAR11: 26.8–29.9 | Barki sheep versus temperate breeds (hot arid environment) [29] | |||
| Small-tailed Han sheep [27] (ecoregion adaptation) | ||||
| CCR17 | Chr15: 74.618–74.636 | OAR15: 72.774–74.55 | HapMap dataset [19] (dairy specialization) | |
| CCR18 | Chr25: 7.356–7.821 | OAR25: 7.517 (peak SNP) | HapMap dataset [21] | |
| OAR25: 7.400–7.600 | Duolang sheep [27] (ecoregion adaptation) | |||