Table 3.
Binary regression analysis of circulating IgG against inflammatory cytokines in T2D
| Antigens | Patient (n) | Control (n) | Adjusted r 2 | p a |
|---|---|---|---|---|
| IL1α | ||||
| Male | 1.15±0.42 (124) | 1.21±0.39 (131) | -0.002 | 0.228 |
| Female | 1.20±0.43 (76) | 1.32±0.39 (89) | 0.009 | 0.083 |
| Combined | 1.17±0.42 (200) | 1.26±0.39 (220) | 0.012 | 0.04 |
| IL1β | ||||
| Male | 0.70±0.28 (124) | 0.77±0.30 (131) | 0.019 | 0.04 |
| Female | 0.78±0.31 (76) | 0.80±0.33 (89) | -0.01 | 0.788 |
| Combined | 0.73±0.29 (200) | 0.78±0.31 (220) | 0.011 | 0.07 |
| IL6 | ||||
| Male | 1.13±0.21 (124) | 1.18±0.19 (131) | 0.01 | 0.038 |
| Female | 1.11±0.23 (76) | 1.24±0.22 (89) | 0.065 | 0.0008 |
| Combined | 1.12±0.22 (200) | 1.20±0.21 (220) | 0.034 | 0.0001 |
| IL8 | ||||
| Male | 0.97±0.35 (124) | 1.02±0.29 (131) | 0.003 | 0.134 |
| Female | 0.94±0.33 (76) | 1.12±0.35 (89) | 0.056 | 0.003 |
| Combined | 0.96±0.34 (200) | 1.06±0.32 (220) | 0.021 | 0.002 |
| TNF-α | ||||
| Male | 0.77±0.40 (124) | 0.95±0.60 (131) | 0.024 | 0.005 |
| Female | 0.85±0.48 (76) | 0.95±0.45 (89) | -0.002 | 0.226 |
| Combined | 0.80±0.43 (200) | 0.95±0.54 (220) | 0.017 | 0.003 |
Data were expressed as mean±SD. aAdjusted for age in male and female samples, and for gender and age in combined samples.