Table 1. Genetic interactions with hmp-1.
| Genotypea | Embryo survival (n) | hmp-1 enhancementb |
|---|---|---|
| % | ||
| Wild type | 98 (555) | N/A |
| gfp-cdc-42 | 99 (387) | N/A |
| gfp-rho-1 | 99 (537) | N/A |
| gfp-ced-10 | 88 (566) | N/A |
| hmp-1(fe4) | 48 (1248) | N/A |
| hmp-1(fe4); gfp-cdc-42 | 19 (273) | Yes |
| hmp-1(fe4); gfp-rho-1 | 19 (160) | Yes |
| hmp-1(fe4); gfp-ced-10 | 46 (434) | No |
| pac-1 | 93 (866) | N/A |
| hmp-1(fe4); pac-1 | 1 (633) | Yes |
| hmp-1(fe4); pac-1; mCherry-pac-1 | 41 (444) | No |
| hmp-1(fe4); pac-1; mCherry-pac-1(R984A) | 0 (479) | Yes |
| picc-1 | 97 (437) | N/A |
| hmp-1(fe4); picc-1 | 14 (498) | Yes |
| pac-1; picc-1 | 92 (573) | N/A |
| jac-1 | 99 (641) | N/A |
| hmp-1(fe4); jac-1 | 0 (726) | Yes |
| jac-1; pac-1 | 70 (918) | N/A |
a
All mutant alleles are functional nulls except the hypomorphic hmp-1(fe4) allele.
b
Yes, P < 0.0001, using the Fisher exact test; No, P > 0.01; N/A, not applicable.