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. 2017 Nov 6;216(11):3485–3495. doi: 10.1083/jcb.201706043

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© 2017 Krüger et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure 3. — Mim1 forms a channel. (A) Current recordings in symmetrical buffer conditions from a bilayer containing active Mim1 channels at the indicated voltage (V_m). (B) Current-voltage recordings of the Mim1 channel in symmetrical buffer conditions. (C) Mean variance plot of a single Mim1 channel unit calculated from the symmetrical current recording (A) at V_m = 120 mV. (D) Current-voltage recordings of the Mim1 channel without (black) or after coreconstitution with Mim2 (red). Mean values of V_rev of five (Mim1) and four (Mim1 + Mim2) independent experiments with SD (unpaired t test). (E) Mean of the maximal current of the Mim1 channel in the absence (n = 15) and presence (n = 11) of Mim2.