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. 2017 Oct 29;23:5150–5157. doi: 10.12659/MSM.904232

Table 3.

LBH589 regulate the expression of caspase-3, APAF-1 and TOSO gene in RRMM-BMMNC (%, χ̄± s).

Groups n Caspase-3 APAF-1 TOSO
24 h 48 h 24 h 48 h 24 h 48 h
Control group 8 1.00±0.00 1.00±0.00 1.00±0.00 1.00±0.00 1.00±0.00 1.00±0.00
20 nmol/L LBH589 8 1.36±0.24a 2.11±0.02a 1.16±0.05a 1.68±0.21a 0.57±0.01a 0.42±0.04a
50 nmol/L LBH589 8 1.68±0.08a 2.81±0.08a 1.58±0.16a 3.74±0.24a 0.43±0.01a 0.12±0.04a

Compared with control group,

a

P<0.05.