Table 3.
Groups | n | Caspase-3 | APAF-1 | TOSO | |||
---|---|---|---|---|---|---|---|
24 h | 48 h | 24 h | 48 h | 24 h | 48 h | ||
Control group | 8 | 1.00±0.00 | 1.00±0.00 | 1.00±0.00 | 1.00±0.00 | 1.00±0.00 | 1.00±0.00 |
20 nmol/L LBH589 | 8 | 1.36±0.24a | 2.11±0.02a | 1.16±0.05a | 1.68±0.21a | 0.57±0.01a | 0.42±0.04a |
50 nmol/L LBH589 | 8 | 1.68±0.08a | 2.81±0.08a | 1.58±0.16a | 3.74±0.24a | 0.43±0.01a | 0.12±0.04a |
Compared with control group,
P<0.05.