Figure 4.

D1/D5 activation on the mPFC did not generate the aversive behavior without white compartment conditioning. (A) Schema of the protocol used. (B) Previous any exposure to the apparatus, animals were infused with D1/5R agonist SKF 38393 in the mPFC and left on their homecage. Test/Pre—test was performed 7 days later. No differences were found in the exploration time of the white compartment (p > 0.05, n = 10–11). (C) Animals were then conditioned only on the black compartment, and infused with D1/5R agonist SKF 38393 in the mPFC immediately after. A new test was performed 7 days later. No differences were found between groups (p > 0.05, n = 10–11).