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. 2017 Oct 30;23:5176–5183. doi: 10.12659/MSM.906680

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© Med Sci Monit, 2017

This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

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C10orf116 copy number was correlated with PTEN copy number and mRNA in PCa. (A) The box plots showed the relationship between mRNA expression and copy number status of C10orf116 gene in prostate tumor. Patients with PCa were divided into 2 subgroups based on their copy number status. (B) Comparison of relationships between mRNA expression and methylation values. Comparison of relationships between C10orf116 copy number and mRNA expression in low-methylation subgroups (C) or high-methylation subgroups (D). P values in the box plot were obtained by t tests (two-tailed). Two scatter plots with regression line in each picture showed an association between copy number and mRNA expression of C10orf116 gene in the low- and high-methylation subgroups. Comparison of relationships between C10orf116 copy number alteration and PTEN copy number (E) or mRNA expression (F).