Table 1.
Identification of genes expressing abnormalities in PCa according to four independent microarrays.
| Gene | Independent microrray data (Fold change) | No. of article* | Association with prostate cancer | ||||
|---|---|---|---|---|---|---|---|
| Direction of regulation | Liu | Vanaja | Varambally | Wallace | |||
| C10orf116 | Down | 2.08 | 2.36 | 2.37 | 2.21 | 1 | A potential prostate cancer biomarker in urinary exosomes [10] |
| AMACR | Up | 5.77 | 8.69 | 10.45 | 2.96 | 132 | Overexpression in prostate adenocarcinomas [13]; growth regulation of PCa [14]; association with biochemical recurrence and poor prognosis [15] |
| TRPM4 | Up | 2.75 | 3.94 | 3.62 | 4.54 | 4 | a novel tissue biomarker [16]; driver gene in androgen-insensitive prostate cancer [17] |
*
No. of articles was based on a search in the PubMed datebase.