Table 4.
The correlation of expression of TAP1 with immune cell markers.
TAP1 expression |
||||
Immune | IRS Front |
IRS Center |
||
markers |
rs |
P-value |
rs |
P-value |
CD3 | 0.297 | <0.001 | 0.240 | <0.001 |
CD8 | 0.215 | <0.001 | 0.154 | 0.003 |
FOXP3 | 0.110 | 0.035 | 0.103 | 0.049 |
Tbet | 0.277 | <0.001 | 0.233 | <0.001 |
NOS2 | 0.234 | <0.001 | 0.202 | <0.001 |
CD163 | 0.298 | <0.001 | 0.262 | <0.001 |
CD66b | 0.018 | 0.729 | 0.012 | 0.818 |
rs, Spearman´s rank correlation coefficient. Total score 3–4, 5–6, 7–12, was used for correlations of CD3, CD8, FOXP3 and Tbet. For NOS2, CD163 and CD66b, score 1–4 at the tumor front was used.